A research team led by Professor Dong Zhang and Guangyong Sun at Beijing Chao-Yang Hospital has identified IFITM1 as a key regulator of the potent anti-tumor activity of TCRαβ⁺CD4^-CD8^- double-negative T cells (DNTs). IFITM1 recruits p62/SQSTM1 to mitochondria and promotes mitophagy, thereby preserving mitochondrial homeostasis, energy metabolism and the tumor-killing capacity of DNTs.

In shale reservoirs, total oil content does not necessarily show where oil is stored or how mobile it may be. Researchers led by Bo Liu at Northeast Petroleum University developed a multiscale workflow that combines swelling-extraction experiments, SEM/AFM pore characterization and molecular dynamics simulations. The study separates shale oil into five occurrence types: kerogen-swelling oil, adsorbed oil in organic pores, free oil in organic pores, adsorbed oil in inorganic pores and free oil in inorganic pores. The framework offers a tool with strong applicability across study areas for understanding oil-rock interactions and evaluating shale-oil mobility in continental shale systems.

A new study published in Science China Earth Sciences presents a comprehensive plan for scientific ocean drilling in the Huatung Basin, a key region in the western Pacific. Researchers propose a four-site drilling strategy for China’s new drilling vessel, Mengxiang, to resolve long-standing debates about the basin's age and the origin of the adjacent Gagua Ridge. The plan aims to determine if the Huatung Basin is a remnant of Mesozoic oceanic crust and to clarify the region's tectonic evolution, marking a potential shift for China’s role in leading international ocean drilling.

Using a highly sensitive two-coil mutual-inductance technique, we systematically track the evolution of the phase stiffness in interfacial superconducting LaAlO₃/KTaO₃(111) and its correlation with the superconducting transition temperature as a function of electrostatic gating. A crossover from Bose–Einstein-condensate-like to Bardeen–Cooper–Schrieffer-like behavior is revealed, suggesting that superconductivity at the two extremes is limited by the establishment of phase coherence and the formation of Cooper pairs, respectively. This behavior is consistent with the emergence of superconducting granularity in two dimensions, which is further supported by the observation of a paramagnetic Meissner effect.

Seawater zinc-air batteries (SZAB) could provide safe, high-energy power for marine applications, but Cl⁻ in seawater can poison the catalysts that drive oxygen reduction reaction (ORR). Researchers from Hainan University and collaborators designed an FeSn dual-single-atom catalysts (FeSn-DSACs) in which Sn neighbors tune Fe active sites through p-d orbital hybridization. The catalyst simultaneously accelerates ORR and suppresses Cl⁻ adsorption and corrosion. In SZAB, it delivered a peak power density of 255.6 mW cm⁻² and operated for more than 500 h, offering a design strategy for durable seawater ORR catalysis.

A data-knowledge dual-driven machine-intelligence framework enables experiment-efficient, full-chain synthesis of 2D dendrites. It achieves rapid process optimization within one week, constructs high-fidelity recipe-morphology mappings, and deciphers multifactorial growth mechanisms, requiring <70 experiments, which covers <1.5% of the total parameter combinations.