An advance toward inhalable mRNA medications, vaccines
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Updates every hour. Last Updated: 26-Apr-2025 19:08 ET (26-Apr-2025 23:08 GMT/UTC)
Most people don’t enjoy getting shots for treatments or vaccines. So, researchers are working to create more medicines, such as those made from messenger RNA (mRNA), that can be sprayed and inhaled. A study in the Journal of the American Chemical Society reports steps toward making inhalable mRNA medicines a possibility. Researchers outline their improved lipid-polymer nanoparticle for holding mRNA that is stable when nebulized and successfully delivers aerosols (liquid droplets) in mice’s lungs.
X-rays are a common component of diagnostic testing and industrial monitoring, used for everything from monitoring your teeth to scanning your suitcase at the airport. But the high-energy rays also produce ionizing radiation, which can be dangerous after prolonged or excessive exposures. Now, researchers publishing in ACS Central Science have taken a step toward safer X-rays by creating a highly sensitive and foldable detector that produces good quality images with smaller dosages of the rays.
As air temperatures stay elevated through fall months, people may still want clothes that cool them down while outside, especially if they live in cities that stay warmer than rural landscapes. Researchers who previously demonstrated a cooling fabric coating now report on additional tests of a treated polyester fabric in ACS Applied Materials & Interfaces. Fabric treated with the team’s chalk-based coating kept the air underneath up to 6 degrees Fahrenheit cooler in warmer urban environments.
Exhaled breath contains chemical clues to what’s going on inside the body, including diseases like lung cancer. And devising ways to sense these compounds could help doctors provide early diagnoses — and improve patients’ prospects. In a study in ACS Sensors, researchers report developing ultrasensitive, nanoscale sensors that in small-scale tests distinguished a key change in the chemistry of the breath of people with lung cancer. November is Lung Cancer Awareness Month.