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Osaka University

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Expression of SEMA7A in human lung adenocarcinoma is regulated by the EGFR-mTOR axis and is involved in development of resistance to EGFR-TKIs. Resistance is mediated by inhibition of apoptosis by the SEMA7A-ITGB1–ERK axis.

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©2018, American Society for Clinical Investigation, <em>JCI Insight</em>. 2018;3(24):e123093. DOI: 10.1172/jci.insight.123093

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