How Immune Systems Change During Aging (IMAGE)

Cincinnati Children's Hospital Medical Center

How Immune Systems Change During Aging

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Undesired excessive Interleukin-10 (IL-10) production in aged mice comes primarily from Tfh cells, according to new findings published in Science Advances. This chart shows that when these cells are stimulated with IL-21, the percentage of IL-10 producing cells rises to 21% in older mice, but just to 9% in younger mice.

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Cincinnati Children's

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