HIV-1 Virus-Like Particles in Lymph Node (IMAGE) eLife Caption The early event of HIV-1 virus-like particles (shown here in green) spreading in the mouse lymph node. Sinus-lining macrophages (cyan) provide a cell-to-cell contact portal to shuttle HIV-1 particles onto follicular dendritic cells (blue) and HIV-1 reactive B cells (red) in the B cell follicle (marked with wild-type B cells, yellow). Credit John Kehrl and Chung Park (CC BY 4.0) Usage Restrictions This image is free to be reused, as long as it is credited appropriately. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.