The Newly Developed Nanobody (IMAGE)

Aarhus University

The Newly Developed Nanobody

Caption

Left panel of the figure displays the structure of the newly developed nanobody (magenta) bound to a C3 fragment called C3b (green). In the right panels, data demonstrating that the nanobody and mutants hereof are able to inhibit the cleavage of C3 in 15 percent human serum. The researchers also constructed a nanobody mutant that completely loses it inhibitory effect on C3 cleavage (purple curve) making it a perfect negative control.

Credit

Rasmus Kjeldsen Jensen and Janus Asbjørn Schatz-Jakobsen, Aarhus University

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