The Rogue T Cells that Drive Multiple Sclerosis (IMAGE)

Boston Children's Hospital

The Rogue T Cells that Drive Multiple Sclerosis

Caption

T helper cells bearing the CXCR6 surface marker drive multiple sclerosis by producing a host of proteins that damage nerve fibers, by attacking their protective myelin sheath. The cells are shown here releasing GM-CSF, which stimulates other immune cells, macrophages, to release damaging inflammatory compounds.

Credit

Lifei Hou/Boston Children's Hospital

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