Nacsa sulfonamides (IMAGE)
Caption
Pharmaceutical companies maintain libraries of chemical compounds that can be screened for use in the development of new drugs. A new photochemical technique, developed by a team led by Penn State chemists, can convert a class of these compounds, known as sulfonamides (bottom), which are difficult to modify for use beyond their initial purpose, into another useful type of compound, anilines (top left). The technique uses simple chemistry to recycle, reuse and repurpose failed drug candidate sulfonamides, which could open new pathways for drug development (top right).
Credit
Eric Nacsa, Penn State
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