Detection efficiency gain and reconstruction workflow of hybrid iterative ptychographic super-resolution microscopy (IMAGE)

Chinese Society for Optical Engineering

Detection efficiency gain and reconstruction workflow of hybrid iterative ptychographic super-resolution microscopy

Caption

Hybrid iterative ptychographic super-resolution microscopy (HiM) significantly improves photon collection efficiency over conventional image scanning microscopy (ISM) and confocal microscopy. Through an alternating virtual modulation-demodulation and sparse joint deconvolution reconstruction algorithm, it achieves favorable resolution enhancement without a depletion laser, while reducing phototoxicity and photobleaching.

Credit

ZHEJIANG UNIVERSITY / YURAN HUANG, HANCHU YE ET AL

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License

CC BY-NC-ND

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