Control theory of aging and longevity for gerotherapeutic drug discovery: state space, vector fields, modalities, safety, and the minimum safe cost of functional restoration (IMAGE)
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Figure 4. Conceptual illustration of loss of controllability with intervention start age. (A) Illustrative reachable safe-set fraction. (B) Illustrative restored-function success fraction under a stricter threshold. The curves and shaded envelopes are schematic and are not estimates or confidence intervals from the five-variable liver simulation.
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Copyright: © 2026 Zhavoronkov and Mishra. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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