Advanced Nucleic Acid Therapeutic with Safe, Robust, Antisense Activity Proposed cholesterol-conjugated PMO/RNA heteroduplex oligonucleotide platform (IMAGE)

Institute of Science Tokyo

Advanced Nucleic Acid Therapeutic with Safe, Robust, Antisense Activity Proposed cholesterol-conjugated PMO/RNA heteroduplex oligonucleotide platform

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Cholesterol-conjugated PMO/RNA heteroduplex oligonucleotide (Chol-HDO[PMO]) achieves high efficacy and high safety, representing a powerful new platform for treating diseases of the central nervous system.

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Institute of Science Tokyo

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