https://www.newswise.com/articles/confirm/855640#:~:text=Exhausted%20Immune%20Cells (IMAGE)
Caption
Immune cells reach head and neck tumors, but many stop working once they arrive (left). Researchers read three things from each cell—which cell it is, its functional state, and the metabolism it uses (center). In laboratory cultures of tumor-infiltrating T cells from untreated patients, researchers blocked the metabolic enzyme G6PD alongside checkpoint inhibitor treatment and studied the effects in the most exhausted cells (right). No patient received the G6PD inhibitor
Credit
Alphonse Laboratory, Johns Hopkins University School of Medicine. Created with BioRender
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