Figure 1. Evidence map of skull bone channel biology. (IMAGE)
Caption
Figure 1: Calvarial SBCs undergo developmental remodeling, are influenced by myeloid and osteoclast-associated pathways involving RANKL and TRPV4, and modulate immune-cell movement from skull marrow to the meninges during neuroinflammation. Solid elements represent findings supported by calvarial studies, whereas dashed elements indicate hypothetical craniomaxillary extensions that require experimental validation.
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Ziwen Sheng, Yulong Zhang, Hao Wang, Wenyu Zhen, Youming Zhu*, Haitao Wang*, Hengguo Zhang*
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