Gallic acid attenuates the malignant phenotype of prostate cancer cells by antagonizing NF-κB/KLF7/L1CAM expression (IMAGE)
Caption
NF-κB p65 can promote the malignant phenotype of prostate cancer (PCa) cells by upregulating KLF7/L1CAM. Gallic acid (GA) can inhibit the transcriptional activation of KLF7 via NF-κB p65, thereby attenuating the malignant phenotype of PCa cells.
Credit
Professors Jun Zhang and Jingzhou Wang from Shihezi University School of Medicine, China; and Dr. Cuizhe Wang from Shihezi University, China
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CC BY-NC-ND