Figure 1. Turning scar-forming cells into neurons after spinal cord injury (IMAGE)

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Figure 1. Turning scar-forming cells into neurons after spinal cord injury

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(A) Illustration of the treatment strategy.

(B) Treatment with TRANsCre-DIONE/Neurog2 resulted in partial recovery up to movement score 3.88/9, while untreated mice remained in near complete paralysis with movement score of below 1/9. Normal mice had reference movement score 9/9.

(C) Left: before injury, Midde two: injured control, Right: injury healed using TRANsCre-DIONE/Neurog2.

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