Hypothalamic–hippocampal neural circuit mediates estrogen-induced memory impairment (IMAGE)

Science China Press

Hypothalamic–hippocampal neural circuit mediates estrogen-induced memory impairment

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Elevated estrogen during pregnancy acts on estrogen receptors in GABAergic neurons within the lateral hypothalamus, increasing firing rates along a projection to the hippocampal CA3 region and leading to temporary memory impairment.

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