KAIST Develops Core Technology to Reverse Biological Changes Once Thought Irreversible, Opening New Possibilities for Aging and Cancer Research (IMAGE)

The Korea Advanced Institute of Science and Technology (KAIST)

KAIST Develops Core Technology to Reverse Biological Changes Once Thought Irreversible, Opening New Possibilities for Aging and Cancer Research

Caption

[Figure 1] The ROOT framework for identifying and controlling the cause of irreversible cell-state transitions

Professor Kwang-Hyun Cho's research team used a logic-based molecular regulatory network to identify the core circuits that sustain irreversible state transitions (the irreversibility kernel), and developed control strategies that either restore cells to their previous state or eliminate irreversibility based on these circuits.

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KAIST

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