KAIST Develops a Way to Combat Cancer Cachexia, the Wasting Syndrome That Debilitates Patients (IMAGE)

The Korea Advanced Institute of Science and Technology (KAIST)

KAIST Develops a Way to Combat Cancer Cachexia, the Wasting Syndrome That Debilitates Patients

Caption

Figure 1. Therapeutic Effects and Phenotypic Improvement in Cancer Cachexia via GFRAL ASO

Target blocking of the GDF15–GFRAL signaling pathway in the brainstem using custom antisense oligonucleotides (ASOs) preserved body weight, muscle mass, fat mass, and muscle function in tumor-bearing mice, significantly extending overall survival.

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KAIST

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