The CCR9-dependent thymic tolerance pathway (IMAGE)

Chiba University

The CCR9-dependent thymic tolerance pathway — Caption

Researchers found that plasmacytoid dendritic cells (pDCs) carry tumor antigens to the thymus in a CCR9-dependent manner, promoting immune tolerance to tumors. The findings identify CCR9 as a potential target for future immunotherapies aimed at strengthening anti-tumor immunity.

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Professor Motoko Y. Kimura from Chiba University, Japan

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