High-resolution molecular typing of Toxoplasma gondii from Chinese wildlife and livestock reveals distinct ToxoDB lineage patterns (IMAGE)

Shanghai Jiao Tong University Journal Center

High-resolution molecular typing of Toxoplasma gondii from Chinese wildlife and livestock reveals distinct ToxoDB lineage patterns

Caption

High-resolution 16-locus MLST of 96 Toxoplasma gondii DNA samples from multiple hosts across China revealed dominance of the ToxoDB#9 lineage with cryptic intra-lineage diversity, high haplotype diversity but limited geographic structuring, and detection of the rare ToxoDB#5 lineage in captive wildlife. These findings support systematic One Health molecular monitoring and future whole-genome sequencing to resolve isolate origins, transmission routes, and recombination.

Credit

Yi-Tian Fu, Yu-Na Xiao, Xi-Long Yi, Hany M. Elsheikha, Bei-Bei Zhou, Meng-Ling Deng, Feng-Cai Zou, Xing-Quan Zhu, Guo-Hua Liu.

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