The RAMPAGE platform accelerates genome evolution in Pichia pastoris by introducing targeted genome-wide mutations during DNA replication (IMAGE)
Caption
The RAMPAGE platform accelerates genome evolution in Pichia pastoris by introducing targeted genome-wide mutations during DNA replication, enabling rapid selection of strains with enhanced methanol tolerance, improved thermotolerance, and alleviated growth defects associated with glycoengineering.
Credit
Yingjia Pan, Zhejiang University
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CC BY-NC-ND