Protein corona dynamics across the blood-brain barrier (IMAGE)

Science China Press

Protein corona dynamics across the blood-brain barrier

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Blood-exposed nanocarriers acquire a protein corona that changes during receptor binding, endothelial uptake, intracellular sorting and release on the brain side. These stage-specific changes may determine whether nanomedicines are cleared, degraded, recycled or productively transported across the blood-brain barrier.

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