PET Imaging Links Brain Metabolism Patterns to Effectiveness of Alzheimer's Disease Treatment (IMAGE)

Society of Nuclear Medicine and Molecular Imaging

PET Imaging Links Brain Metabolism Patterns to Effectiveness of Alzheimer's Disease Treatment

Caption

Figure 1. Cerebral metabolic patterns of Alzheimer's Disease (AD, top row), Limbic-Predominant Age-Related TDP-43 Encephalopathy (LATE, middle row), and Dementia with Lewy Bodies (DLB, bottom row). The non-AD group was comprised of patients with LATE and DLB cerebral metabolic patterns. After 1 year of anti-amyloid therapy, the AD group's MoCA significantly increased by 1.75 0.96 points (p=0.035) while the non-AD group's MoCA significantly decreased by 5.00 2.71 points (p=0.035). There is a significant difference in the change in MoCA scores between AD and non-AD groups (p = 0.01).

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Image courtesy of SNMMI.

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