Vitamin K-Dependent GAS6 Signaling Regulates Bone Resorption in Male Mice (IMAGE)

Editorial Office of West China School of Stomatology, Sichuan University

Vitamin K-Dependent GAS6 Signaling Regulates Bone Resorption in Male Mice

Caption

Genetic inactivation of γ-carboxylation in osteoblasts increased trabecular bone mass and reduced osteoclast activity in male mice, revealing a vitamin K-dependent GAS6 signaling pathway that regulates bone resorption.

Credit

Dr. Mathieu Ferron from Institut de recherches cliniques de Montréal, Canada Image Source Link: https://doi.org/10.1038/s41413-026-00528-2

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