Biological differences among agricultural fungicide-induced evolved strains (IMAGE)

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Biological differences among agricultural fungicide-induced evolved strains

Caption

Stably drug-resistant strains were screened and obtained via serial in vitro passaging under the stress of stepwise gradient drug concentrations (left panel). The resulting drug-resistant strains exhibited significant phenotypic heterogeneity in colony morphology and cell size. Whole-genome copy number variation (CNV) analysis of all strains revealed that all drug-resistant strains harbored segmental chromosomal amplifications of varying degrees.

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Mycology-An International Journal on Fungal Biology

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