Stage-dependent transcriptomic changes in human dermal fibroblast senescence model (IMAGE)
Caption
Figure 7. Senescence-stage-dependent expression patterns of representative genes. Violin plots showing transcript expression levels (TPM) of nine selected genes across three senescence stages: young, middle, and old. Genes include IFIT1, MX1, OAS1 (Meta2), EIF3CL, EEF1D, RPLP2 (Meta4), and MMP9, SULF1, PCDHGB2 (Meta6). Each plot displays the distribution and individual data points. Statistical significance was assessed using one-way analysis of variance followed by Tukey’s post-hoc test. Asterisks indicate significant differences between groups: *p < 0.05, **p < 0.01, ***p < 0.001.
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Copyright: © 2026 Kudo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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