260429-Kyogoku-Competition-2_pronuclei (IMAGE)
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In mammals such as mice and humans, the DNA-carrying nuclei of these cells don’t fuse right away but remain separate as so-called “pronuclei” until just before the first cell division. This 3D-reconstructed image shows a mouse zygote (fertilized egg), where maternal (magenta) and paternal (green) genomes are enclosed in separate pronuclei. “This fact has been known for decades, but no one really understood why this separation exists,” says Kobe University developmental biologist KYOGOKU Hirohisa.
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KYOGOKU Hirohisa
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