Design and lymphatic imaging workflow of MPEG-PCL@ME microneedles. (IMAGE)

Burns & Trauma

Design and lymphatic imaging workflow of MPEG-PCL@ME microneedles.

Caption

Design and lymphatic imaging workflow of MPEG-PCL@ME microneedles. Schematic illustration of the preparation and application of the MPEG-PCL@ME imaging system. (a) Methylene blue is encapsulated into MPEG-PCL nanoparticles through a double-emulsion process to form the lymphatic tracer MPEG-PCL@ME. (b) The tracer is delivered intradermally by dissolvable microneedles, enters lymphatic vessels in the rat tail, and enables near-infrared visualization of lymphatic vessels and lymph nodes.

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Burns & Trauma

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