DOCK10 in Insulin Hypersecretion in Human Insulinoma (IMAGE)

Institute of Science Tokyo

DOCK10 in Insulin Hypersecretion in Human Insulinoma

Caption

Comprehensive analyses of surgical insulinoma specimens and patient-derived organoids identified DOCK10 as a regulator of abnormal insulin secretion. Functional studies in organoids and xenograft models supported the therapeutic relevance of the DOCK10–Cdc42 axis.

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Institute of Science Tokyo

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