ether phospholipids enhance the sensitivity of touch sensor PIEZO and warmth sensor TRPA1 by altering physical properties of the cell membranes. (IMAGE)

National Institutes of Natural Sciences

ether phospholipids enhance the sensitivity of touch sensor PIEZO and warmth sensor TRPA1 by altering physical properties of the cell membranes.

Caption

This modulation is essential for maintaining normal somatosensory responses mediated by these sensory molecules. When ePLs are depleted, avoidance behaviors against mechanical stimulation and warmth temperature become blunted.

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Takaaki Sokabe

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