Figure 1 (IMAGE)
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Transitions of tonic inhibition in cerebellar granule cells during adolescence. Astrocyte-released GABA (green) increases, spillover GABA (red) from inhibitory neurons (Golgi cells) decreases, while GABA uptake by transporters (blue) becomes more effective. A set point voltage (reversal potential) for GABA-activated inhibitory current decreases, enhancing GABA’s inhibitory action.
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Institute for Basic Science
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