Improving Drug Solubility Using Porous Carrier Substances (IMAGE)
Caption
These plots show powder X-ray diffraction measurements of three different types of formulations: simple mixing (a, d), the conventional evaporation/condensation method (b, e), and the proposed sealed heating method (c, f). As seen in the bottom row, formulations of 90% mesoporous silica and 10% ibuprofen reach an amorphous state with either of the two methods, evidenced by the lack of diffraction peaks corresponding to drug crystals.
Credit
Professor Takehisa Hanawa from Tokyo University of Science, Japan Image link: https://doi.org/10.1016/j.xphs.2025.104140
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License
CC BY