Study on how the behavior of poloxamer mixtures evolves depending on temperature and concentration (IMAGE)

Chiba University

Study on how the behavior of poloxamer mixtures evolves depending on temperature and concentration

Caption

Schematic illustration of the temperature-dependent self-assembly and sol–gel transition behavior of mixed poloxamer 407 (P407) and poloxamer 188 (P188) systems. The diagram summarizes the evolution from unimers to micelles and further micellar packing upon heating, highlighting the non-straightforward shifts of the sol–gel transition temperature (Tsol–gel) as a function of P188 content. The proposed mechanism is supported by in situ small-angle X-ray scattering (SAXS), temperature-sweep rheology, and differential scanning calorimetry (DSC), linking molecular self-assembly to macroscopic gel formation.

Credit

Associate Professor Kenjirou Higashi from Chiba University, Japan

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