Global Prevalence, Temporal Trends, and Associated Mortality of Bacterial Infections in Patients with Liver Cirrhosis (IMAGE)
Caption
BIs are common in patients with liver cirrhosis and show a modest upward trend over time, with the highest burdens observed in ACLF and notable regional variation. Gastrointestinal infections, SBP and UTI predominate, gram-negative organisms are more frequent than gram-positive organisms, and MDR pathogens are significant. Importantly, infections are associated with a higher mortality, underscoring the need for improved diagnostic approaches and standardized research frameworks to deliver clearer guidance for the clinical management of patients with liver cirrhosis.
Credit
Yu-Chen Fan, Yu-Xin Tian
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License
CC BY-NC