Phenotype characterisation at the end of 16 weeks on diets for FXRhep flox/flox and FXRhep-/- mice. (IMAGE)

First Hospital of Jilin University

Phenotype characterisation at the end of 16 weeks on diets for FXRhep flox/flox and FXRhep-/- mice.

Caption

 (A) Female and male body weight change over the course of 16 weeks for FXRhep flox/flox and FXRhep-/- (B) Female and male liver-to-body weight ratios; (C) H&E stained liver sections (n=3–6); (D) Female (left) and male (right) LW/BW ratios. Data are represented as mean±SD (n = 4–15) in panels A, B and D. Two-way ANOVA. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001. ANOVA, analysis of variance; CTL, low-fat control diet; FF, fast food; FXR, farnesoid X receptor; LW/BW, liver weight-to-body weight; UDCA, ursodeoxycholic acid.

Credit

By Grace L Guo et al.

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CC BY-NC

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