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Higher Education Press

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Under HFD challenge, the expression levels of FBLN7 in progenitor cells of adipose tissues were dramatically upregulated. FBLN7 interacts with TSP1, leading to the activation of latent TGFβ1. This, in turn, promotes the TGFβ/Smad signaling pathway, ultimately exacerbating adipose tissue fibrosis and metabolic dysfunction.

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HIGHER EDUCATON PRESS

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