A biophysically detailed simulation of the whole mouse cortex neuron by neuron, with sub-cellular resolution (IMAGE)
Caption
Biophysically detailed simulation of the whole mouse cortex neuron by neuron, with sub-cellular resolution—that is, capturing ion flows and fluctuations of membrane voltage within many compartments that the tree-like neuronal morphologies consist of. Neurons are colored by cortical area and marked with a light flash when active. Only 1% of neurons are shown for clarity. The simulation represents “spontaneous” activity of the cortex in a resting state.
Credit
Barry Isralewitz1, with contributions by Kaaya Akira-Tamura2, Kael Dai3, Laura Green3, Beatriz Herrera3, Tadashi Yamazaki2, and Anton Arkhipov3 using the simulation from the paper: Kuriyama et al., Microscopic-Level Mouse Whole Cortex Simulation Composed of 9 Million Biophysical Neurons and 26 Billion Synapses on the Supercomputer Fugaku, Proc. of the Int. Conf. for High Perf. Computing, Networking, Storage and Analysis (SC ’25), St. Louis, MO. 1 University of Illinois at Urbana-Champaign, Urbana, IL, USA 2 University of Electro-Communications, Tokyo, Japan 3 Allen Institute, Seattle, WA, USA
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