Mechanisms of radiation-induced brain injury at different post-radiotherapy time points (IMAGE)

Xia & He Publishing Inc.

Mechanisms of radiation-induced brain injury at different post-radiotherapy time points

Caption

Radiotherapy induces DNA damage and oxidative stress, leading to endothelial injury and blood-brain barrier disruption, which triggers neuroinflammation, microvascular dysfunction, and neuronal apoptosis, ultimately resulting in progressive edema, demyelination, and irreversible brain necrosis. Created with BioRender.com. ROS, reactive oxygen species.

Credit

Xiaonan Cui

Usage Restrictions

Credit must be given to the creator. Only noncommercial uses of the work are permitted.

License

CC BY-NC

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.