Sakaguchi defines a new class of T cells (IMAGE)

Scripps Research Institute

Sakaguchi defines a new class of T cells

Caption

Sakaguchi defined a new class of T cells by showing that the T cells with CD25 on their surface protected against autoimmune diseases through an experiment in mice that lacked T cells. If he injected CD4-bearing T cells into the mice, but removed all the cells with CD25, the mice developed serious autoimmune diseases. If he added CD25-bearing cells, the mice remained health.

Credit

© The Nobel Committee for Physiology or Medicine. Ill. Mattias Karlén

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