Prognostic biomarkers discovery pipeline via machine learning. (IMAGE)
Caption
Prognostic biomarkers discovery pipeline via machine learning. (A) Workflow of NB prognostic biomarker discovery and related downstream analyses. (B) Heatmap showing gene expression patterns of prognostic biomarkers derived through machine learning. (C) KEGG pathway enrichment analysis of biomarkers. (D) GO pathway enrichment analysis of biomarkers. (E) Venn diagram showing overlap between machine learning-derived prognostic biomarkers and driver genes identified in the literature. GO, gene ontology; KEGG, Kyoto Encyclopedia of Gene Genomes; NB, neuroblastoma; scRNA-seq, single-cell RNA sequencing; WGCNA, weighted gene co-expression network analysis.
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Pediatric Discovery
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