NUFIP1 in Sepsis: Regulating Immune Function and Organ Dysfunction. (IMAGE)
Caption
NUFIP1 in Sepsis: Regulating Immune Function and Organ Dysfunction. This illustration demonstrates the pivotal role of NUFIP1-mediated ribophagy in dendritic cell activation and sepsis-induced immune suppression. It shows how NUFIP1 mitigates ER stress, enhances dendritic cell function, and influences the immune response during sepsis. The figure also highlights the progression of immune dysfunction, leading to multiple organ failure, and suggests that NUFIP1 is a potential therapeutic target for improving sepsis outcomes.
Credit
Burns & Trauma
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CC BY-NC