Flow chart of production of fertilizable sperm from rat ES cells by the blastocyst complementation method (IMAGE)

Niigata University

Flow chart of production of fertilizable sperm from rat ES cells by the blastocyst complementation method

Caption

Using the blastocyst complementation method, we produced rat embryonic stem (ES) cell-derived sperm in testicular hypoplasia mice and successfully generated rat offspring. This method can provide a cost-effective and efficient strategy for generating genetically modified rats, addressing various problems in genetic engineering with rats.

Credit

Niigata University

Usage Restrictions

The image may only be used with appropriate caption or credit.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.