Imagen (IMAGE)

Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)

Imagen

Caption

TEVs-TTN is a tool that permits the controlled cleavage of titin in mice. The confocal and electron microscopy images show that titin cleavage in muscle triggers disassembly of sarcomeres, and the staining with hematoxylin and eosin (H&E) and succinate dehydrogenase (Mitochondria) reveal myofibril atrophy, nuclear internalization, and mitochondrial aggregation. Image partially created with BioRender.com

Credit

CNIC

Usage Restrictions

No restrictions.

License

Public Domain

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