A collagen-based 3D-bioprinted tissue scaffold perfused within a 3D printed bioreactor to achieve vascular-like nutrient delivery in engineered tissues. (IMAGE)
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Online cover of Science Advances, April issue. A collagen-based 3D-bioprinted tissue scaffold perfused within a 3D printed bioreactor to achieve vascular-like nutrient delivery in engineered tissues. Previous designs posed bioengineering challenges as they traditionally used plastic and elastomers that are stiff and difficult to engineer. Shiwarski et al. developed a 3D bioprinting method to create soft, living tissues that develop internal vascular networks. They printed pancreatic tissues that can sense glucose and release insulin, potentially transforming treatments for type 1 diabetes and human organ manufacturing.
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Credit: Daniel Shiwarski
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