Research Spotlight: Basal Cell Carcinoma’s Low Immunogenicity is Associated with Suppression of Antigen Presentation Stemming from its Cell of Origin (IMAGE)

Mass General Brigham

Research Spotlight: Basal Cell Carcinoma’s Low Immunogenicity is Associated with Suppression of Antigen Presentation Stemming from its Cell of Origin

Caption

Basal cell carcinoma has low immunogenicity. Tumor cells express Foxc1 protein (red), which suppresses HLA class I (green) in the tumor cells.

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Shawn Demehri, Massachusetts General Hospital

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