18F-Fallypride PET Imaging (IMAGE)

Society of Nuclear Medicine and Molecular Imaging

18F-Fallypride PET Imaging

Caption

Figure 3. PET results. (A) 18F-fallypride displacement in vmPFC. Single-sample t test of γ-maps yielded significant voxels in vmPFC (Tmax = 13.8; cluster size, 528 voxels; peak voxel coordinates, 4, 36, −10; familywise error rate–corrected P < 0.001) and amplitudes of 18F-fallypride displacement in this cluster of voxels of γ = 0.022 ± 0.006 min−1 for all included participants. (B) Negative correlation between 18F-fallypride displacement γ in vmPFC and response time–based switch costs from behavioral analyses (cluster 1: Tmax = 3.25; cluster size, 9; peak voxel coordinates, −8, 28, −8; P < 0.005) (cluster 2: Tmax = 3.11; cluster size, 5; peak voxel coordinates, −12, 20, −16; P < 0.005). (C) Negative correlation between 18F-fallypride displacement γ in vmPFC and error rate–based switch costs from behavioral analyses (Tmax = 3.08; cluster size, 18; peak voxel coordinates, 8, 26, −14; P < 0.005). Color scales show T-values.

Credit

Images created by Isabelle Miederer, Hans-Georg Buchholz, Mathias Schreckenberger, Department of Nuclear Medicine, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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