Polarized dual view lightsheet microscope (IMAGE)
Caption
The polarized diSPIM microscope, which can image full 3D orientation and position of molecules in cells. The instrument was constructed in the Hari Shroff lab at the National Institute of Biomedical Imaging and Bioengineering (NIBIB) after the idea was conceived at the Marine Biological Laboratory, Woods Hole. Liquid crystals used for polarized illumination are shown in green circles. The diSPIM’s dual-view paths meet at a right angle on the sample. See Chandler et al., PNAS, 2025.
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Min Guo
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