Fig. 1 (IMAGE)
Caption
Selenoproteins safeguard stemness of hematopoietic stem cells and B-lineage maturation. Disrupted selenoprotein synthesis recapitulated aged phenotype. The accumulation of lipid peroxidation accelerated by aging occurs in specific cellular contexts and lineages. Under such oxidative stress, B cell progenitors acquire myeloid characteristics. (Created in BioRender. Yamazaki, H. (2025) https://BioRender.com/ w92d562)
Credit
Yumi Aoyama
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