Anti-tumor activity of AgNPs and AgNP-Cx+ against melanoma (IMAGE)

Pensoft Publishers

Anti-tumor activity of AgNPs and AgNP-Cx+ against melanoma

Caption

Anti-tumor activity of silver nanoparticles (AgNPs) and chlorhexidine-silver nanoparticles conjugates (AgNP-Cx+) against melanoma. Legend: ζ-zeta potential – characterizes the charge of the silver nanoparticles; dH hydrodynamic diameter – the size that the particles acquire in an aqueous dispersion; HaCaT – normal cells, human keratinocytes; SH-4 – tumor cells, human melanoma; IC50 – the concentration that inhibits cell proliferation at 50%; SD – standard deviation of the values based on six repetitions of the experiment; ppm – part per million; Selectivity Index – an index that is calculated as the quotient of IC50 on normal cells and IC50 on tumor cells; the greater its value, the more selective the agent against the cancer cells; p-value – statistical indicator; the lower the value the greater the statistical significance between the results obtained with the different samples; a borderline for significance is normally set at p<0.05; n/a – not applicable.

Credit

Nadezhda Ivanova

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License

CC BY

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