Volcano plots and functional enrichment analyses of the upregulated and downregulated differentially expressed genes (DEGs). (IMAGE)

Xia & He Publishing Inc.

Volcano plots and functional enrichment analyses of the upregulated and downregulated differentially expressed genes (DEGs).

Caption

This figure presents the volcano plots for visualizing DEGs (a) and the functional enrichment analyses (b-d) for upregulated and downregulated DEGs in the immune non-responder (INR) group vs. healthy control (HC) group (b), INR group vs. immune responder (IR) group (c), and IR group vs. HC group (d). (a) Blue dots represent downregulated genes, and red dots represent upregulated genes. The x-axis represents the log2 fold change in gene expression, indicating the degree of upregulation (positive values) or downregulation (negative values). The y-axis represents the -log10 of the adjusted P-value, with higher values indicating greater statistical significance. (b-d) The x-axis shows the enriched terms (biological processes, cellular components, molecular functions, or pathways), and the y-axis represents the -log10 of the adjusted P-value, indicating the significance of enrichment. DEGs, differentially expressed genes; HC, healthy control; IR, immune responder; INR, immune non-responder.

Credit

ong Zhang, Zhen Li, Yang Zhang, Jiahao Ji

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License

CC BY-NC

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